Grenade can refer to:
- Mk 2 Grenade - the hand grenade used in Half-Life and its expansions
- MK3A2 Grenade - the hand grenade used in Half-Life 2 and its episodes
- Combine Grenade - a grenade used in Half-Life: Alyx
- Xen Grenade - another grenade used in Half-Life: Alyx
- Flash Grenade - the grenade cut from Half-Life: Opposing Force
- Energy Grenade - the grenade cut from Half-Life 2
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