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"It's your old friend, deadly neurotoxin. If I were you, I'd take a deep breath. And hold it."

The Neurotoxin Generator is a large creation chamber used for the mass-production of neurotoxin, a highly noxious gas that can be distributed throughout the facility for defensive purposes. The generator is located in a large industrial area deep down in the Aperture Science Enrichment Center, near the Employee Daycare Center.


The Neurotoxin Generator is a massive cylinder housed within a large room deep underground in the Enrichment Center. Eight large hoses attached allow the gas to be distributed through the Aperture Science Pipe Network to any location throughout the facility. Its storage capacity is presumably large enough for its contents to cover the entire facility, which is how GLaDOS killed almost all of the employees.

The Neurotoxin Generator is the second objective in Chell and Wheatley's plan to nullify GLaDOS' defenses. After disrupting the turret production lines, Wheatley and Chell make their way to the generator, which Wheatley then attempts to "hack". As he has no idea what he's doing, Chell has to disable it by using portals and a Thermal Discouragement Beam to severe the hoses. This causes the pressure within the container to drop to "Dangerously unlethal levels". The container then implodes and falls apart. Subsequently, a vent on a nearby wall breaks open, drawing in Chell and Wheatley.


  • This is one of, if not the only, instance(s) in the game where portals can be placed on moving panels without disappearing.
  • Despite the Neurotoxin Generator being completely destroyed by Chell and Wheatley early on in the game, Wheatley is still able to use Neurotoxin in the final battle. In the room with the science projects just before the neurotoxin room there is a potato plant that has overgrown into the ceiling. It is possible this could be where he got the neurotoxin from, as potatoes can produce solanine, a natural neurotoxin.
  • The sign that says to look at the implosion was added due to play-testers not looking at the generator implosion animation.
  • Neutotoxins are considerably less lethal in the Portal franchise. In both games, it is shown that Chell could survive for six minutes. This doesn't seem to apply in one specific condition; in Portal 2, GLaDOS attempted to lure Chell to a testing area where she claimed that a "deer" is present for Chell to interact. As soon as Chell enters the area, the panels will lock her in and neurotoxin will flood the room, killing her after a minute. This could be because the room this event took place in is much smaller than the two other rooms where neurotoxin is used, mainly GLaDOS and Wheatley's chambers.
  • In a deleted quote from Wheatley, he explains the existence of a Neurotoxin Release Button. He used to work alongside the guard overseeing the button, but was eventually fired, either because of his clumsiness and/or, according to Wheatley, not being popular with the others (This was likely removed to avoid speculation of Wheatley flooding the Enrichment Center on Bring Your Daughter to Work Day instead of GlaDOS).


List of appearances[]